MANUKA HONEY SCIENTIFIC EVIDENCE


Scientific Evidence for the Health Benefits of Medical-Grade Manuka Honey

For centuries, honey has been used in traditional healing practices—but today, modern science is confirming what ancient cultures always knew: honey, especially medical-grade Manuka honey, offers powerful health benefits.

Recent peer-reviewed clinical studies have shown that medicinal Manuka honey, rich in MGO (Methylglyoxal), contains potent antibacterial, antimicrobial, and anti-inflammatory properties. These properties make it one of the most studied and trusted natural remedies available today.

At Biosota Organics, we produce premium, science-backed Manuka honey that is tested and verified for purity, potency, and therapeutic value.

Below, you'll find links to reputable scientific journals featuring peer-reviewed, evidence-based research that supports the health benefits of Manuka honey.

medicinal honey

ANTIBACTERIAL & ANTIVIRAL



ANTIVIRAL BENEFITS OF MANUKA HONEY


Antiviral and Immunomodulatory Effects of Phytochemicals from Honey against COVID-19:


Anti-influenza viral effects of honey in vitro: potent high activity of manuka honey:


In vitro antiviral activity of honey against VZV: A medicine study for potential remedy for shingles:


ANTIBACTERIAL BENEFITS OF MANUKA HONEY


Therapeutic Manuka Honey:


Antibacterial effect of Manuka honey on Clostridium difficile:


Killing of Six Common Wound Pathogens With Manuka Honey Dressings:


The unusual antibacterial activity of medical-grade Leptospermum honey:



Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains:


Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka:


Secondary Bacterial Infections Associated with Influenza Pandemics:

Author: Denise E. Morris, David W. Cleary, and Stuart C.Clarke
Published: 23 June, 2017
Link: Secondary Bacterial Infections Associated with Influenza Pandemics

Effect of Honey, Dextromethorphan, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents:

Authors: Ian M. Paul, MD, MSc; Jessica Beiler, MPH; Amyee McMonagle, RN
Published: December, 2007
Link: Effect of Honey, Dextromethorphan, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents

Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections:

Author: Victoria C. Nolan, James Harrison, John E. E. Wright, Jonathan A. G. Cox
Published: 31 October, 2020
Link: Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections: A Systematic Review

ANTI-INFLAMMATORY & ANTI-OXIDANT


ANTIINFLAMMATORY BENEFITS OF MANUKA HONEY


Protective effects of Manuka honey:

Authors: Massimiliano Gasparrini, Sadia Afrin, Tamara Y Forbes-Hernández, Danila Cianciosi, Patricia Reboredo-Rodriguez, Adolfo Amici, Maurizio Battino, Francesca Giampieri
Published: 2 August, 2018
Link: Protective effects of Manuka honey on LPS-treated RAW 264.7 macrophages.
Part 2: Control of oxidative stress induced damage, increase of antioxidant enzyme activities and attenuation of inflammation


ANTIOXIDANT BENEFITS OF MANUKA HONEY


Manuka honey attenuates oxidative damage:


Manuka honey protects middle-aged rats from oxidative damage:

CANCER


BENEFITS OF MANUKA HONEY FOR CANCER


Intravenous Administration of Manuka Honey Inhibits Tumor Growth and Improves Host Survival When Combined with Chemotherapy:


Manuka honey synergistically enhances the chemopreventive effect on human colon cancer cells:


Effectiveness of honey on radiation-induced oral mucositis among patients with head and neck malignancies:


Oxidative stress, inflammation, and cancer: how are they linked?:


Inhibition of STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey:


Signaling Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer Cells:

CYSTIC FIBROSIS


BENEFITS OF MANUKA HONEY FOR CYSTIC FIBROSIS


Manuka honey in the treatment of cystic fibrosis-associated chronic rhinosinusitis:

IMMUNE SUPPORT


BENEFITS OF MANUKA HONEY FOR IMMUNE SUPPORT


Mānuka honey-derived methylglyoxal enhances microbial sensing by T cells:

GASTRIC ULCERS & GUT HEALTH


BENEFITS OF MANUKA HONEY FOR STOMACH ULCERS


Molecular Mechanisms of Natural Honey Against H. pylori Infection:


BENEFITS OF MANUKA HONEY FOR GUT HEALTH


The susceptibility of gastrointestinal pathogens to the antibacterial effect of manuka honey:

ORAL HEALTH & SINUSITUS



BENEFITS OF MANUKA HONEY FOR ORAL HEALTH


Effect of Manuka honey on the clinical levels of dental plaque:


Antibacterial potential of Manuka honey against three oral bacteria:

Author: Patrick R Schmidlin, Helen English, Warwick J Duncan, Georgios N. Balibasakis
Published: September, 2014
Link: Antibacterial potential of Manuka honey against three oral bacteria in vitro


The effects of manuka honey on plaque and gingivitis: a pilot study:


BENEFITS OF MANUKA HONEY FOR SINUSITIS


Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial:


The association of Leptospermum honey with cytokine expression of chronic rhinosinusitis patients:

WOUNDS & SKIN CARE


BENEFITS OF MANUKA HONEY FOR WOUNDS


Acceptability to patients of a honey dressing for non-healing venous leg ulcers:


Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies:


Resolution of folliculitis decalvans with medical honey:


Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers:


Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration:


What Makes Biosota Organics Manuka Honey Medicinal?

The difference lies in the MGO content. Manuka honey’s healing power is measured by its concentration of Methylglyoxal—a naturally occurring compound responsible for its antimicrobial potency. Our medicinal Manuka honey is:

  • Rich in MGO for strong antibacterial activity

  • Packed with bioactive compounds like flavonoids and phenolic acids

  • Certified and independently tested for authenticity and efficacy

  • Free from glyphosate, GMOs, and synthetic additives

This powerful combination supports the treatment and prevention of a wide range of conditions, including:

  • Minor burns and wounds

  • Skin infections and irritations

  • Oral and dental care

  • Sore throats, coughs, and cold symptoms

  • Digestive health and gut balance

  • Immune system support

  • General wellness and vitality

The higher the MGO rating, the stronger the honey’s therapeutic potential. Biosota offers some of the highest MGO-rated Manuka honey in the world, including rare MGO 2200+ for serious immune and health support.

medicinal honey

Tested. Verified. Trusted.

At Biosota Organics, our dedication to quality is backed by science. Every batch of our high-strength Manuka honey is independently tested in independent accredited laboratories to confirm MGO levels and medicinal bioactivity.

We combine generations of beekeeping expertise with the latest scientific research to bring you one of the most powerful natural health products available today.



Download Our Research-Based Fact Sheets

Download our fact sheets below to learn more about the clinically proven health benefits of medical-grade Manuka honey. 

MANUKA HONEY STRENGTH CHART


Manuka Honey Strength Chart